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目的:探讨慢性阻塞性肺疾病稳定期应用玉屏风颗粒联合金水宝胶囊治疗的临床效果。方法:将120例慢性阻塞性肺疾病稳定期患者随机分为西药常规治疗组(Ⅰ组,n=40)、西药加玉屏风颗粒联合金水宝胶囊治疗组(Ⅱ组,n=40)及西药加舒利迭吸入治疗组(Ⅲ组,n=40),比较其临床疗效。结果:与治疗前比较,治疗后6个月、1年Ⅱ组IgA(g/L)水平明显提高(P<0.05),其它组变化不明显(P<0.05);治疗后6个月、1年Ⅱ组FEV1/FVC值明显改善(P<0.05),其它组间变化无明显差异(P>0.05);Ⅱ组治疗后6个月、1年急性发作次数低于其它两组,无住院病例,Ⅰ组再住院率为7.5%,Ⅲ组为5%;三组均无死亡病例发生。结论:慢性阻塞性肺疾病稳定期应用玉屏风颗粒联合金水宝胶囊治疗,可提高免疫力,改善肺功能,防范急性复发,具有非常重要的临床价值。
Objective: To investigate the clinical effect of Yupingfeng granule combined with Jinshuibao capsule in the treatment of chronic obstructive pulmonary disease in stable period. Methods: One hundred and twenty patients with chronic obstructive pulmonary disease (COPD) were randomly divided into two groups: group Ⅰ (n = 40), group Yupingfeng granules combined with jinshuibao capsule (group Ⅱ, n = 40) Gasseria into inhalation group (group Ⅲ, n = 40), compared its clinical efficacy. Results: Compared with those before treatment, the level of IgA (g / L) in group Ⅱ increased significantly (P <0.05) at 6 months and 1 year after treatment, but not in other groups (P <0.05) The FEV1 / FVC values in group Ⅱ were significantly improved (P <0.05), but there was no significant difference among the other groups (P> 0.05). In group Ⅱ, the number of acute attacks at 6 months and 1 year was lower than the other two groups, , The rehospitalization rate of group Ⅰ was 7.5% and that of group Ⅲ was 5%. No deaths occurred in the three groups. Conclusion: Yupingfeng granule combined with Jinshuibao capsule can improve immunity, improve lung function and prevent acute recurrence in the stable stage of chronic obstructive pulmonary disease. It has very important clinical value.