我院自1991年以来,对应用扩冠药钙阻滞剂及抗凝药等治疗无效的二例重度不稳定型心绞痛病人,用尿激酶治疗后取得明显疗效,现将治疗情况报告如下。 病例选择:本文报道的二例冠心病不稳定型、重度心绞痛,均符合1981年全国心血管专业组会议的诊断标准。 尿激酶治疗方法:治疗前后检查血常规、血小板计数、凝血时间、凝血酶原时间及纤维蛋白原。本文二例治疗时用尿激酶20～40万u加于5％葡萄糖注射液100ml中静滴,每次一小时滴完,一天一次,共二天。治疗后用肝素或口服抗凝药维持5～7天。 例1:男性,64岁,住院号138305。因劳累后心悸、胸闷二周,于1991年5月9日入院。有高血压病史20余年,过去无胸痛史。近二周每当活动或上楼梯时即感心悸、胸闷痛,每次持续5～15分钟,休息后能缓解。近二天来胸闷痛持续时间较前延长,最长 In our hospital since 1991, two cases of severe unstable angina pectoris patients with coronary heart disease such as coronary heart disease, coronary heart disease and coronary heart disease have been treated with urokinase. The treatment is reported as follows. Case Selection: Two cases of unstable coronary heart disease, severe angina pectoris reported in this paper are in line with the diagnostic criteria of the 1981 national cardiovascular professional group meeting. Urokinase treatment: before and after treatment check blood, platelet count, clotting time, prothrombin time and fibrinogen. Two cases of this treatment with urokinase 20 ~ 400 000 u plus 5% glucose injection 100ml intravenous drip, every hour drops, once a day, a total of two days. After treatment with heparin or oral anticoagulant to maintain 5 to 7 days. Example 1: Male, 64 years old, hospital number 138305. Due to fatigue after palpitations, chest tightness two weeks, on May 9, 1991 admission. Have a history of hypertension more than 20 years, no history of chest pain in the past. Nearly two weeks whenever the activities or up the stairs when feeling palpitations, chest pain, each lasting 5 to 15 minutes after the rest can ease. Chest tightness in the past two days longer duration of the extension, the longest