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以0.1% 桔黄Ⅳ为指示剂,采用pH 指示剂吸收度比值法测定甲硝唑的含量,RSD 小于0.2% ,结果满意。与非水滴定法的结果比较,差值在0.3% 之内。
The content of metronidazole was determined by the ratio of absorbance of pH indicator with 0.1% orange Ⅳ as indicator, with RSD less than 0.2%. The results were satisfactory. Compared with the non-aqueous titration method, the difference is within 0.3%.