The process of 180° domain switching in PbTiO3 single crystal under an antiparallel electric field was investigated by the three-dimensional phase field simulation, especially the effect of electric field on the type and duration of domain switching. It is found that the polarization reversal of domains takes place under an antiparallel electric field in PbTiO3 single crystal. The results of the phase field simulation indicate that there is only 90° domain switching under a weak electric field. With the rise of the electric field, 180° domainswitching appears. If the electric field is strengthened further, 90° domain switching disappears and the duration of domain switching is shortened.