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目的为研究慢性肾炎患者红细胞免疫粘附功能、T细胞亚群与cGMP的相关关系,探讨cGMP作为慢性肾炎免疫功能指标的临床意义。方法将53例慢性肾炎患者细胞免疫粘附功能、T细胞亚群与cGMP进行直线相关回归分析。结果cGMP与RBC-C3bRR呈负相关,与RBC-ICR呈正相关,与CD3呈负相关,与CD4呈负相关。结论cGMP可能是免疫调节的重要信使,cGMP检查可以较准确的反映机体两种细胞免疫功能。
Objective To study the relationship between erythrocyte immune adherence function and T cell subsets and cGMP in patients with chronic nephritis and to explore the clinical significance of cGMP as an immunological function indicator of chronic nephritis. Methods 53 cases of chronic glomerulonephritis patients with cell adhesion function, T cell subsets and cGMP linear regression analysis. Results cGMP was negatively correlated with RBC-C3bRR, positively correlated with RBC-ICR, negatively correlated with CD3, and negatively correlated with CD4. Conclusion cGMP may be an important messenger of immune regulation, cGMP can accurately reflect the two kinds of cellular immune function.