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目的评价自由基清除剂依达拉奉治疗急性脑梗死的疗效。方法92例急性脑梗死患者分为依达拉奉治疗组和对照组,每组46例。分别对两组治疗前、治疗后第7、14、30天进行神经功能缺损评分及治疗第30天疗效评价。结果治疗组治疗后各时期神经功能缺损评分均显著低于对照组(P<0.05,P<0.01),治疗第30天治疗组和对照组的总有效率分别为86.9%和69.6%(P<0.05)。结论早期应用依达拉奉治疗急性脑梗死能显著促进患者神经功能恢复,降低伤残率,提高生活质量。
Objective To evaluate the efficacy of free radical scavenger edaravone in the treatment of acute cerebral infarction. Methods 92 patients with acute cerebral infarction were divided into edaravone treatment group and control group, 46 cases in each group. The neurological deficit score and the curative effect on the 30th day of treatment were evaluated before treatment, 7th, 14th and 30th days after treatment. Results After treatment, the neurological deficit scores of the treatment group were significantly lower than those of the control group (P <0.05, P <0.01). The total effective rates of the treatment group and the control group on the 30th day of treatment were 86.9% and 69.6%, respectively (P < 0.05). Conclusion The early use of edaravone in the treatment of acute cerebral infarction can significantly promote the recovery of neurological function, reduce the disability rate and improve the quality of life.