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目的探讨心脏再同步化治疗(CRT)对慢性充血性心力衰竭(CHF)的临床疗效以及心脏超声结合组织多普勒检查对患者筛选和疗效评价的作用。方法10例CHF患者,接受CRT术前及术后行超声心动图及组织多普勒检查,以评价心功能及心脏收缩不同步指标,并指导术中左室电极的植入。结果术后6～12个月随访较术前比,左室舒张末内径(LVEDD)[(6.45±0.80)cmvs.(6.89±0.40)cm]明显减小;左室射血分数(LVEF)[(44.80±8.40)%vs.(29.00±2.20)%]明显增加;心脏收缩不同步指标也明显改善。结论CRT可改善左室功能,逆转左室重构;超声心动图结合组织多普勒技术是筛选患者及评价疗效的有效方法。
Objective To investigate the clinical efficacy of cardiac resynchronization therapy (CRT) in the treatment of chronic congestive heart failure (CHF) and the effect of cardiac ultrasonography combined with tissue Doppler examination on screening and efficacy evaluation. Methods Ten patients with CHF underwent echocardiography and Tissue Doppler echocardiography before and after CRT to evaluate cardiac function and systolic asynchrony and to guide intraoperative left ventricular electrode implantation. Results The LVEDD [(6.45 ± 0.80) cm vs. (6.89 ± 0.40) cm] at 6-12 months postoperatively was significantly lower than that before the operation. The left ventricular ejection fraction (LVEF) (44.80 ± 8.40)% vs (29.00 ± 2.20)%], and systolic cardiac systolic index was significantly improved. Conclusions CRT can improve left ventricular function and reverse left ventricular remodeling. Echocardiography combined with tissue Doppler technique is an effective method for screening patients and evaluating curative effect.