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乌苏烷型降三萜是在乌苏烷三萜碳骨架上减少1个或几个甲基,按其缺少甲基的位置可分为23-降、24-降、28-降、29-降、30-降、2-降、3-降和3,24-降8种类型。其药理活性包括抗癌、抗炎、抗菌和抑制酰基辅酶A-胆固醇酰基转移酶(ACAT)等。结合国内外有关乌苏烷型降三萜类化合物的文献,对乌苏烷型降三萜类化合物的植物分布、化学结构特征及药理活性3方面进行综述,为此类化合物的进一步研究提供参考依据。
Ursuline-type triterpenoids in the wushane triterpenoid carbon skeleton to reduce one or several methyl, according to their lack of methyl can be divided into 23-down, 24-down, 28-down, 29- Down, 30-down, 2-down, 3-down and 3,24-down 8 types. Its pharmacological activities include anti-cancer, anti-inflammatory, antibacterial and inhibit acyl-CoA-cholesterol acyltransferase (ACAT) and so on. Combining domestic and foreign literatures on nostane-typed triterpenoids, the plant distribution, chemical structure and pharmacological activities of nosoot-typed triterpene compounds are summarized, which provide reference for further research on these compounds in accordance with.