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目的分析血浆中D-二聚体(D-dimer,D-D)水平在血栓性疾病的临床意义。方法随机抽取2016年1月—2016年6月在新疆维吾尔自治区人民医院就诊的32例脑梗塞患者(脑梗塞组)和30例肺栓塞患者(肺栓塞组)作为研究对象,另将同期30例体检健康者作为对照组,分别检测两组血浆中D-D水平并进行统计学分析。结果脑梗塞组和肺栓塞组血浆D-D水平分别为(5.02±6.03)mg/L和(4.88±5.84)mg/L,均高于对照组(0.26±0.14)mg/L,差异有统计学意义(P<0.05)。结论血浆D-D是血液高凝状态和纤溶亢进的特异性指标,对血栓性疾病的早期诊断和及时治疗有一定的临床意义。
Objective To analyze the clinical significance of plasma D-dimer (D-D) level in thrombotic diseases. Methods Thirty-two patients with cerebral infarction (cerebral infarction group) and 30 patients with pulmonary embolism (pulmonary embolism group) were selected randomly from January 2016 to June 2016 in People’s Hospital of Xinjiang Uygur Autonomous Region. Another 30 patients Healthy people as a control group, respectively, test two groups of plasma DD levels and statistical analysis. Results Plasma DD levels in cerebral infarction group and pulmonary embolism group were (5.02 ± 6.03) mg / L and (4.88 ± 5.84) mg / L, respectively, which were significantly higher than those in control group (0.26 ± 0.14) mg / L (P <0.05). Conclusions Plasma D-D is a specific index of blood hypercoagulability and fibrinolysis and has some clinical significance for the early diagnosis and timely treatment of thrombotic diseases.