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目的:了解抗感染药物引起的不良反应,为临床用药提供警示。方法:对我院收集到的513例抗感染药物引起的不良反应病例报告进行分类统计和分析评价。结果:引起不良反应的药物共有72个品种,其中氨基糖苷类药居首位(114例,占22.22％),其次为青霉素类(107例,占20.86％)、头孢菌素类(97例,占18.91％)、喹诺酮类药物(86例,占16.76％)。不良反应的分类以皮肤及附件损害最为常见,其次为神经系统和消化系统的损害。 结论:应合理使用抗感染药物,减少不良反应的发生。
Objective: To understand the adverse reactions caused by anti-infective drugs and provide a warning for clinical use. Methods: We collected 513 cases of anti-infectives in our hospital cases of adverse reactions caused by the classification statistics and analysis and evaluation. Results: A total of 72 kinds of drugs caused adverse reactions, of which aminoglycosides ranked the first (114 cases, accounting for 22.22%), followed by penicillins (107 cases, accounting for 20.86%), cephalosporins (97 cases, Accounting for 18.91%), quinolones (86 cases, accounting for 16.76%). Adverse reactions to the classification of skin and accessories damage the most common, followed by the nervous system and digestive system damage. Conclusion: Anti-infectives should be used rationally to reduce the incidence of adverse reactions.