论文部分内容阅读
[目的]探讨乳酸脱氢酶(LDH)与胃癌分期之间的关系。[方法]检测不同分期胃癌患者及健康对照者血清LDH值的变化,探讨其与胃癌及胃癌分期之间的联系及机制。[结果]胃癌患者组血清LDH[(314.32±7.45)U/L]明显高于正常对照组[(199.47±4.67)U/L],P<0.05,胃癌Ⅳ期患者LDH值[(352.76±8.03)U/L]较Ⅰ、Ⅱ、Ⅲ期患者LDH值[(297.17±13.03)、(301.68±6.24)、(313.15±9.16)U/L]明显升高(P<0.05)。[结论]远处转移的胃癌患者的LDH水平明显高于未发生远处转移的患者,LDH检测可用于胃癌转移状况的辅助诊断方法和病期判断的指标。
[Objective] To investigate the relationship between lactate dehydrogenase (LDH) and gastric cancer staging. [Methods] The changes of serum LDH levels in patients with gastric cancer at different stages and healthy controls were examined, and their relationship with gastric cancer and staging of gastric cancer were explored. [Results] Serum LDH [(314.32 ± 7.45) U / L] in gastric cancer patients was significantly higher than that in controls ([199.47 ± 4.67] U / L], P < ) U / L] were significantly higher than those in patients with stage Ⅰ, Ⅱ and Ⅲ [(297.17 ± 13.03), (301.68 ± 6.24), (313.15 ± 9.16) U / L] [Conclusion] LDH levels in patients with distant metastasis of gastric cancer are significantly higher than those in patients without distant metastasis. The LDH test can be used as an auxiliary diagnosis method and indicator of disease stage of gastric cancer metastasis.