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目的:观察小儿牛黄清心散联合西药治疗手足口病的疗效。方法:200例手足口病患儿按住院号分为观察组和对照组各100例。对照组采用西医抗病毒,维持水电解质平衡,保持呼吸道通畅,支持对症治疗。观察组在此基础上加服小儿牛黄清心散。两组疗程均为I周。观察两组患儿治疗3 d、7 d后体温及症状变化情况,比较两组疗效。结果:观察组痊愈率及总有效率均明显高于对照组(P<0.01)。两组患者治疗3 d、7 d后,观察组体温正常病例以及手、足、口腔等部位斑丘疹、疱疹消失率+好转率等指标均明显优于对照组(P<0.01)。治疗过程中,观察组无病情恶化病例,对照组6例患儿进入第2期,两组差异有统计学意义(P<0.05)。结论:小儿牛黄清心散联合西药治疗手足口病疗效肯定,值得临床推广应用
Objective: To observe the curative effect of pediatric bezoar xinxin powder combined with western medicine on hand-foot-mouth disease. Methods: 200 cases of hand, foot and mouth disease patients were divided into observation group and control group according to the hospital number of 100 cases. The control group used Western antiviral drugs to maintain water and electrolyte balance, maintain airway patency, and support symptomatic treatment. On the basis of observation group plus pediatric bezoar Qingxin San. Two groups of treatment are I weeks. The changes of body temperature and symptoms of the two groups were observed after 3 days and 7 days of treatment, and the curative effect was compared between the two groups. Results: The cure rate and total effective rate in observation group were significantly higher than those in control group (P <0.01). After 3 days and 7 days of treatment, the two groups of patients with normal body temperature and rash in the hands, feet and mouth, herpes disappearance rate and improvement rate were significantly better than those in the control group (P <0.01). During the course of treatment, there were no cases of exacerbation in the observation group and 6 cases of the control group entered the second period. The difference between the two groups was statistically significant (P <0.05). Conclusion: Pediatric Niu Huang Qing Xin San combined with Western medicine treatment of hand, foot and mouth disease is effective, worthy of clinical application