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目的探讨老年念珠菌性阴道炎采用硝酸咪康唑和伊曲康唑治疗的效果对比。方法回顾分析90例患者的临床资料。结果观察组45例中,治疗1w后总有效率为97.8%,治疗4w后总有效率为95.6%。对照组45例中,治疗1w后总有效率为80%,治疗4w后总有效率为71.1%。观察组治疗效果明显优于对照组,差异有统计学意义(P<0.05)。治疗期间两组各有2例出现食欲减退、轻度恶心和头晕症状,停药后均自行消失。结论老年念珠性阴道炎采用伊曲康唑进行治疗,使用方便、安全有效、不良反应低、疗程短,明显提高了临床效果,改善了患者生存质量。
Objective To investigate the effect of miconazole nitrate and itraconazole in the treatment of elderly candidal vaginitis. Methods The clinical data of 90 patients were retrospectively analyzed. Results In the observation group of 45 cases, the total effective rate was 97.8% after 1 w of treatment, and the total effective rate was 95.6% after 4 w of treatment. In the control group of 45 cases, the total effective rate was 80% after 1 w of treatment, and the total effective rate was 71.1% after 4 w of treatment. Observation group was significantly better than the control group, the difference was statistically significant (P <0.05). Two patients in each group experienced loss of appetite, mild nausea and dizziness in two patients during treatment, and all disappeared after stopping the treatment. Conclusions Senile rosary vaginitis is treated with itraconazole. It is easy to use, safe and effective, has low adverse reactions and short course of treatment, which obviously improves the clinical effect and improves the quality of life of the patients.