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目的:通过测定血清心肌肌钙蛋白I(cTnI)探讨血清cTnI对小儿病毒性心肌炎(VMC)心肌损害的早期诊断价值。方法:对VMC组31例,疑似VMC组30例及非心脏疾病的患儿对照组23例测定血清cTnI和心肌酶谱肌酸磷酸激酶CK及其同工酶CK-MB,并将3种结果进行比较。结果:VCM组cTnI、CK、CK-MB均明显高于疑似VMC组、对照组的cTnI均正常。结论:血清的cTnI早期诊断小儿VMC较CK-MB具有更高的特异性和敏感性。
Objective: To investigate the value of serum cTnI in the early diagnosis of myocardial damage in children with viral myocarditis (VMC) by measuring serum cardiac troponin I (cTnI). Methods: Serum cTnI and creatine phosphokinase CK and its isoenzyme CK-MB were detected in 31 cases of VMC group, 30 cases of suspected VMC group and 23 cases of non-cardiac disease control group. Three kinds of results Compare. Results: The cTnI, CK and CK-MB in VCM group were significantly higher than those in suspected VMC group, while the cTnI in control group were all normal. Conclusion: Serum cTnI early diagnosis of children with VMC than CK-MB has a higher specificity and sensitivity.