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目的:探讨安多明在糖尿病视网膜病变中的治疗效果。方法:番禺中心医院2009年1月至2010年12月糖尿病视网膜病变3～5期患者108人,完全随机分2组:治疗组(54例105眼,激光联合安多明治疗),对照组(54例102眼,激光治疗)。治疗前后行视力、眼底以及行荧光造影检查,根据视力检查标准以及荧光造影标准判定治疗效果进行统计学分析。结果:糖尿病视网膜病变3、4期患者,治疗组的有效率明显大于对照组(P<0.05);糖尿病视网膜病变5期患者,治疗组及对照组的有效率差异无统计学意义(P>0.05)。结论:糖尿病视网膜病变1～4期患者可采用安多明或激光辅以安多明治疗,5期患者,安多明的治疗效果并不明显,激光及手术治疗尤为重要。
Objective: To investigate the therapeutic effect of Andomintin in diabetic retinopathy. Methods: One hundred and eighty patients with diabetic retinopathy from March 2009 to December 2010 were randomly divided into two groups: treatment group (54 cases, 105 eyes, laser combined with amodamine treatment), control group ( 54 cases 102 eyes, laser treatment). Visual acuity, ocular fundus and fluoroscopy were performed before and after treatment. Statistical analysis was made according to the standard of visual acuity and standard of fluoroscopy. Results: The effective rate of diabetic retinopathy in patients with stage 3 and 4 was significantly higher than that of the control group (P <0.05). There was no significant difference in the effective rate between the diabetic retinopathy and the control group (P> 0.05) ). Conclusion: Patients with stage 1 ~ 4 diabetic retinopathy may be treated with amiodarone or laser combined with amodamine. In the 5 patients, the effect of amlodipine is not obvious, and laser and surgical treatment are particularly important.