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目的评估慢性肾脏病(CKD)合并高血压患者盐分摄入量与降压药的关系。方法选取200例CKD合并高血压患者,记录患者体质量、身高、年龄等数据,检测患者血肌酐(Scr),计算患者肾小球滤过率估计值(e GFR)。记录患者降压药的用量,分析食盐的摄入与降压药的关系。结果已知需要控制盐摄入的143例患者中有53例患者尿钠达到标准(即尿钠<100 mmol/d)。分析表明,尿钠水平与降压药用量呈正相关(分别为r=0.63、0.67,均P<0.01)。结论 CKD合并高血压患者降压药使用量与其食盐摄入量密切相关。限制CKD患者食盐的摄入工作亟待加强、量化,并定期进行检测和指导,在必要时给予干预。
Objective To evaluate the relationship between salt intake and antihypertensive drugs in patients with chronic kidney disease (CKD) and hypertension. Methods 200 patients with CKD and hypertension were enrolled in this study. The body mass, height and age of the patients were recorded. The serum creatinine (Scr) was measured and the estimated glomerular filtration rate (e GFR) was calculated. Record the amount of antihypertensive drugs in patients, analysis of the relationship between salt intake and antihypertensive drugs. Results Of the 143 patients who were required to control salt intake, 53 of the 143 patients achieved a standard urinary sodium (Na + <100 mmol / d). Analysis shows that the level of sodium and antihypertensive drugs were positively correlated (r = 0.63,0.67, respectively, P <0.01). Conclusions The use of antihypertensive drugs in CKD patients with hypertension is closely related to their salt intake. Restrictions on salt intake in patients with CKD need to be strengthened, quantified, and regular testing and guidance, if necessary, to intervene.