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采用紫外分光光度法和高效液相色谱法对吡喹酮缓释片的溶出度进行了测定.两种方法的测定结果基本一致。2h 溶出度是25.27±6.04%(UV)和25.80±5.49%(HPLC),3h 溶出度是72.80±4.21%(UV)和77.32±2.96%(HPLC),5h 溶出度是91.69±3.43%(UV)和92.41±4.16%(HPLC)。
The dissolution of praziquantel sustained-release tablets was determined by ultraviolet spectrophotometry and high performance liquid chromatography.The results of the two methods were basically the same. The 2h dissolution was 25.27 ± 6.04% (UV) and 25.80 ± 5.49% (HPLC), the 3h dissolution was 72.80 ± 4.21% (UV) and 77.32 ± 2.96% (HPLC), the 5h dissolution was 91.69 ± 3.43% ) And 92.41 ± 4.16% (HPLC).