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38例的骨髓(BM)及外周血(PB)分别作了铁、过碘酸—雪夫氏(PAS)与过氧化酶(POX)染色。铁染色32例,3/4的病例铁粒幼细胞>60％,7例环状铁粒幼细胞>BM有核细胞15％,但外铁均正常。转急白与否和大量环状铁粒幼细胞的出现未见明显关系。PAS染色31例,28例(90％)幼红细胞呈阳性反应。各型MDS幼红细胞虽均有阳性反应,但RA阳性细胞百分数与积分低(<5％)。红系有巨变者,幼红细胞PAS阳性细胞百分数与积分较高,这一结果与Di—Guglielmo′s综合征表现相似,据此可与巨幼细胞性贫血鉴别。PB作POX染色15例,有半数以上病例的中性粒细胞部分缺乏POX活性。
38 cases of bone marrow (BM) and peripheral blood (PB) were made of iron, periodic acid - Schiff (PAS) and peroxidase (POX) staining. Iron staining in 32 cases, 3/4 cases of iron granulocytes> 60%, 7 cases of annular mitochondria> 15% of BM nucleated cells, but the iron are normal. There was no significant correlation between acute white or not and the appearance of a large number of annular mitochondria baby cells. PAS staining in 31 cases, 28 cases (90%) of erythroblasts positive. Although all kinds of MDS erythroblasts have positive reaction, the percentage of RA positive cells is low (<5%). There was a big change in erythroid, erythrocyte PAS positive cells with higher percentage and integral, this result and Di-Guglielmo’s syndrome similar performance, which can be identified with megaloblastic anemia. PB for POX staining in 15 cases, more than half of the cases of neutrophil lack of POX activity.