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测定了４９ 例急性心肌梗塞（ Ａ Ｍ Ｉ） 患者治疗前、后血浆心钠素（ Ａ Ｎ Ｐ） 的水平。结果表明， 治疗前 Ａ Ｎ Ｐ 测定值为４０５ ．５４ ±１２７ ．４１ ｐｇ／ｍ Ｌ， 治疗后为３４２ ．３４ ±１３０ ．５１ｐｇ／ ｍ Ｌ。而对照组为２７５ ．１１ ±１２０ ．６３ｐｇ／ ｍ Ｌ。两组相比，前者差别非常显著（ Ｐ＜ ０ ．０１） ，后者差别亦显著（ Ｐ＜０ ．０５） 。 Ａ Ｍ Ｉ组治疗后 Ａ Ｎ Ｐ 水平明显下降， 与治疗前比较差别显著（ Ｐ＜ ０ ．０５） 。本文对此做了讨论， 提出 Ａ Ｍ Ｉ 时 Ａ Ｎ Ｐ 的增高可能与心室顺应性改变和心功能不全以及心肌受损有关， 是保护内环境稳定的一种代偿机制。
The plasma atrial natriuretic peptide (ANP) levels were measured in 49 patients with acute myocardial infarction (AMI) before and after treatment. The results showed that pre-treatment A N P measured value of 405. 54 ± 127. 41 pg / m L, 342 after treatment. 34 ± 130. 51pg / m L. While the control group was 275. 11 ± 120. 63pg / m L. The difference between the two groups was significant (P <0.01), and the difference between the two groups was also significant (P <0.05). The level of A N P in A M I group after treatment was significantly lower than that before treatment (P <0 .05). This article made a discussion, put forward A M I A N P increase may be related to changes in ventricular compliance and cardiac dysfunction and myocardial damage related to the protection of the internal environment is a compensatory mechanism.