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脑动脉瘤模型的建立有多种方法,弹性蛋白酶诱导建立脑动脉瘤模型的制作方法日益被广泛应用,该方法操作方便、周期短,组织病理结构也接近于临床人动脉瘤。本文回顾弹性蛋白酶诱导脑动脉瘤的制作方法,并阐明其在建立脑动脉瘤模型方面的意义,为进一步研究动脉瘤的发生发展和转归预后提供良好的实验平台。
There are many ways to establish the model of cerebral aneurysm. Elastase-induced establishment of a model of cerebral aneurysm is increasingly widely used. The method is easy to operate, has a short cycle and has a histopathological structure similar to that of a clinical aneurysm. This article reviews elastase-induced cerebral aneurysm production methods, and clarify its significance in the establishment of cerebral aneurysm model, in order to further study the occurrence and development of aneurysms and prognosis provide a good experimental platform.