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我们应用超剂量地塞米松冲击治疗肾病综合征12例,现报告如下: 临床资料根据1985年南京会议关于修订肾小球疾病临床分型的意见,12例中属原发性肾病综合征Ⅰ型9例,Ⅱ型3例。发病时间3个月～10年。12例均曾接受肾上腺皮质激素治疗,其中曾用大剂量地塞米松(每日0.5～1mg/kg,最大剂量不超过50mg)3天为一个疗程未能缓解3例,2个疗程未能缓解1例,以强的松每日1mg/kg连用8周不能
We apply overdose of dexamethasone shock treatment of nephrotic syndrome in 12 cases, are as follows: Clinical data According to the 1985 Nanjing meeting on the revision of the clinical classification of glomerular disease advice, 12 cases of primary nephrotic syndrome type Ⅰ 9 cases, Ⅱ type in 3 cases. Incidence of 3 months to 10 years. 12 cases were treated with adrenal cortex hormones, which had a large dose of dexamethasone (daily 0.5 ~ 1mg / kg, the maximum dose of not more than 50mg) 3 days for a course failed to alleviate 3 cases, 2 courses failed to alleviate 1 case, with prednisone 1mg / kg daily for 8 weeks can not