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目的:探讨不同年龄段儿童巨幼细胞性贫血(Megaloblastic anemia,MA)的病因。方法:分析14例巨幼细胞性贫血患儿的临床资料,总结不同年龄组患儿的发病特点。结果:所有病例均为农村儿童,其中年龄小于3岁的11例患儿中均伴有不同程度的喂养不当史;有10例为纯母乳喂养,有2例患儿母亲为素食者。>3岁的3例患儿中,2例为严重偏食,不食肉、蛋、奶类食物,1例为癫痫患儿,发病前口服苯巴比妥3年。结论:巨幼细胞性贫血在农村仍有散发病例,营养因素仍是儿童巨幼细胞性贫血的主要病因;大年龄组患儿的病因除营养因素以外还需注意其他病因。
Objective: To investigate the etiology of megaloblastic anemia (MA) in children of different ages. Methods: The clinical data of 14 children with megaloblastic anemia were analyzed. The incidence characteristics of children with different age groups were summarized. Results: All cases were rural children, of which 11 were less than 3 years of age were accompanied by varying degrees of improper feeding history; 10 cases were exclusively breastfeeding, 2 cases of mothers with children as vegetarians. > 3-year-old 3 cases of children, 2 cases of severe partial eclipse, do not eat meat, eggs, milk food, 1 case of epilepsy children, before the onset of oral phenobarbital 3 years. CONCLUSION: Megaloblastic anemia is still sporadic in rural areas. Nutritional factors are still the major cause of childhood megaloblastic anemia. The causes of children with large age group should pay attention to other causes besides nutritional factors.