Ⅰ型(胰岛素依赖型)糖尿病患者,尽管用胰岛素替代治疗,仍常见肝内及周围组织内糖代谢受损。这种胰岛素抵抗与病程长短有关。Ⅰ型糖尿病患者中约40%应用“功能性”胰岛素替代治疗,严格控制血糖使 HbA_(1c)维持在正常范围以后,可使胰岛素抵抗得以改善,但这一结果并不意味着糖代谢的正常化。至今曾有报告Ⅰ型糖尿病患者与健康者相比,在 Type I (insulin-dependent) diabetes mellitus, despite insulin replacement therapy, is still commonly impaired in the liver and surrounding tissues. This insulin resistance and the duration of the disease. Approximately 40% of patients with type 1 diabetes use “functional” insulin replacement therapy. Strict glycemic control of HbA_ (1c) may improve insulin resistance, but this does not imply that glucose metabolism Normalization. To date, there have been reports of type 1 diabetes compared with healthy people