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目的:观察经皮肾动脉支架置入术(PTRAS)前后老年难治性高血压患者的临床效果。方法:选择2010年9月至2011年9月在郑州市中医院心内科住院治疗的30例难治性高血压患者,经肾动脉造影确诊为动脉粥样硬化性肾动脉狭窄,同时行肾动脉支架置入术,观察介入治疗前、后其血压、服药数量及肾功能变化情况。结果:手术成功率为100%,无手术并发症。收缩压由术前(180±15)mmHg降至(138±8)mmHg(1mmHg=0.133kPa),舒张压由(110±16)mmHg降至(87±6)mmHg(P<0.01),口服降压药物由(4±2片)降至(1±1)片(P<0.01),肌酐和尿素氮在手术前后无明显差异。结论:PTRAS是目前治疗老年难治性高血压的有效方法,具有安全、简便的优点。
Objective: To observe the clinical effect of elderly patients with refractory hypertension before and after percutaneous renal artery stent implantation (PTRAS). Methods: From September 2010 to September 2011 in Zhengzhou City Hospital of Cardiology inpatient treatment of 30 patients with refractory hypertension, renal artery angiography was diagnosed as atherosclerotic renal artery stenosis, while the renal artery Stent implantation was performed to observe the changes of blood pressure, medication dosage and renal function before and after interventional therapy. Results: The success rate of surgery was 100%, no surgical complications. Systolic blood pressure decreased from (180 ± 15) mmHg to (138 ± 8) mmHg (1 mmHg = 0.133 kPa) and diastolic pressure decreased from (110 ± 16) mmHg to (87 ± 6) mmHg The antihypertensive drugs decreased from (4 ± 2) tablets to (1 ± 1) tablets (P <0.01). Creatinine and urea nitrogen had no significant difference before and after operation. Conclusion: PTRAS is an effective method for the treatment of elderly refractory hypertension, which has the advantages of safety and simplicity.