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目的探讨垂体后叶素加硝酸甘油治疗肝硬化合并急性食管胃底静脉曲张破裂出血的临床疗效。方法对82例出血患者采用垂体后叶素+硝酸甘油(治疗组)和单纯垂体后叶素(对照组)治疗,比较2组止血效果和并发症。结果治疗组、对照组在止血效果方面差异无统计学意义(P>0.05),但并发症发生率差异有统计学意义(P<0.01)。结论在用垂体后叶素止血的同时,运用硝酸甘油,可减轻垂体后叶素带来的副作用,加大垂体后叶素的治疗剂量,可以增加其止血效果。
Objective To investigate the clinical efficacy of vasopressin plus nitroglycerin in the treatment of liver cirrhosis complicated with acute esophageal variceal bleeding. Methods 82 hemorrhagic patients were treated with pituitrin + nitroglycerin (treatment group) and pituitrin alone (control group). The hemostatic effects and complications of the two groups were compared. Results There was no significant difference in the hemostatic effects between the treatment group and the control group (P> 0.05). However, the incidence of complications was statistically significant (P <0.01). Conclusions In the use of vasopressin hemostasis, the use of nitroglycerin can reduce the side effects of vasopressin and increase the therapeutic dose of pituitrin can increase its hemostatic effect.