目的探讨新生儿血糖异常的病因及防治措施。方法对存在血糖异常高危因素的565例新生儿进行血糖监测,其中低血糖184例,高血糖20例,对血糖异常的相关因素进行分析。结果早产儿及小于胎龄儿、新生儿窒息、颅内出血、医源性因素、喂养困难、感染、糖尿病母亲娩出儿等患儿低血糖发生率较高;医源性因素、颅内出血、糖尿病母亲娩出儿、巨大儿等患儿高血糖发生率较高。结论高危新生儿易发生糖代谢紊乱,对高危新生儿应常规进行血糖监测,及早采取防治措施。 Objective To investigate the etiology and prevention and treatment of neonatal abnormal blood glucose. Methods Blood glucose was monitored in 565 newborns with high risk of abnormal blood sugar, including 184 cases of hypoglycemia and 20 cases of hyperglycemia. The related factors of abnormal blood glucose were analyzed. Results The prevalence of hypoglycemia in preterm infants and infants less than gestational age, neonatal asphyxia, intracranial hemorrhage, iatrogenic factors, feeding difficulties, infection and delivery of mothers with diabetes were higher. Iatrogenic factors, intracranial hemorrhage, diabetic mothers Childbirth, giant children with high incidence of hyperglycemia. Conclusion High-risk neonates are prone to disorder of glucose metabolism, blood glucose monitoring should be routinely carried out in high-risk neonates and early prevention and treatment measures should be taken.