论文部分内容阅读
目的:探讨纳洛酮鞘内注射治疗中重型颅脑损伤的疗效。方法:对纳洛酮治疗的79例中重型颅脑损伤患者进行回顾性分析,总结并比较纳洛酮鞘内注射、静脉滴注及对照组伪疗效。结果:纳洛酮鞘内注射组在提高治愈率、降低致残率及植物状态生存率、缩短伤后平均昏迷时间较静滴及对照组疗效显著(P<0.01)。结论:鞘内注射纳洛酮治疗中重型颅脑损伤疗效肯定,且优于静脉滴注。
Objective: To investigate the efficacy of intrathecal injection of naloxone in the treatment of moderate-severe craniocerebral injury. Methods: A total of 79 patients with severe craniocerebral injury treated with naloxone were retrospectively analyzed. The effects of intrathecal injection of naloxone, intravenous drip and the control group were summarized and compared. Results: In the intrathecal Naloxone group, the cure rate, the morbidity reduction, the plant state survival rate and the mean postoperative coma duration were significantly shorter than those in the control group and the intravenous injection group (P <0.01). Conclusion: Intrathecal injection of naloxone in the treatment of moderate and severe craniocerebral injury is effective and superior to intravenous drip.