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目的了解宫颈糜烂患者单纯疱疹病毒(HSV)感染状况。方法用抗原捕获聚合酶链反应(AC-PCR)对450份妇女宫颈棉拭标本进行HSV检测与分型。结果HSV的检出率为25.5%(115/450),其中HSV-1和HSV-2的检出率分别为6.4%(29/450)和19.1%(86/450)。宫颈糜烂组和正常对照组的检出率分别为30.2%(100/331)和12.6%(15/119),两组间检出率差异有统计学意义(χ2=14.26,P<0.005)。随宫颈糜烂程度的增加,HSV感染率增加。结论HSV感染与宫颈糜烂的发生密切相关,以HSV-2感染为主。
Objective To understand the status of herpes simplex virus (HSV) infection in patients with cervical erosion. Methods HSV detection and typing were performed on 450 cervical swabs from women with antigen capture polymerase chain reaction (AC-PCR). Results The detection rate of HSV was 25.5% (115/450). The detection rates of HSV-1 and HSV-2 were 6.4% (29/450) and 19.1% (86/450) respectively. The detection rates of cervical erosion group and normal control group were 30.2% (100/331) and 12.6% (15/119), respectively. There was significant difference between the two groups (χ2 = 14.26, P <0.005). With the increase of cervical erosion, HSV infection rate increased. Conclusions HSV infection is closely related to the occurrence of cervical erosion, mainly HSV-2 infection.