2001年,国际血栓与止血学会(ISTH)的科学标准化委员会(SSC)将弥散性血管内凝血(DIC)定义为“一种获得性凝血功能紊乱综合征”。它的特点是不同病因引起的血管内凝血活化,其凝血紊乱可源于微血管损伤亦可导致微血管损伤,严重情况下可致使器官功能衰竭[1]。2012年,DIC诊断与治疗中国专家共识在上述定义基础上融入了“微血管体系损伤”的概念,提出了新的DIC概念,即DIC是在许多疾病基础上,致病因素损伤微血管体系,导 In 2001, ISTH’s Scientific Committee for Standardization (SSC) defined disseminated intravascular coagulation (DIC) as “an acquired coagulopathy syndrome.” It is characterized by different causes of intravascular coagulation activation, coagulation disorders can be derived from microvascular damage can also lead to microvascular damage, severe cases can cause organ failure [1]. In 2012, the Chinese expert consensus on diagnosis and treatment of DIC integrated the concept of “microvascular damage” into the above definition and proposed a new concept of DIC, which is based on many diseases. Pathogenic factors damage the microvascular system, guide