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患者男性,27岁,因浸潤型肺結核于1961年3月1日入院,既往无腰痛及血尿史。在入院的第二日突然出現腹泻、腹痛,大便1日4次,含粘液及血,鏡检有大量紅細胞及脓細胞。患者經每6小时服磺胺脒2克,3日后症状减輕,5日后腹痛消失,但于服药后第7日总量达52克时发現尿色发紅、腰痛,无尿頻及排尿痛,两側腎区有叩打痛。尿呈酸性,蛋白(++),鏡检紅細胞滿視野,并有大量无色透明长方形的磺胺結晶。当即停服磺胺脒,給予大量重碳酸鈉口服,并囑患者多飲水。
Male patient, 27 years old, was admitted to hospital on March 1, 1961 for infiltrating pulmonary tuberculosis. He never had any history of back pain and hematuria. On the second day of admission, sudden diarrhea, abdominal pain, stool on the 1st 4 times, with mucus and blood, microscopic examination of a large number of red blood cells and pus. Patients with sulfamethoxazole 2 grams every 6 hours after 3 days to reduce the symptoms, abdominal pain disappeared after 5 days, but on the 7th day after the total amount of 52 grams and found urine color redness, low back pain, no frequent urination and urination pain, Kidney area on both sides knocking pain. Urinary acidity, protein (++), microscopic examination of red blood cells over the field of vision, and a large number of colorless transparent rectangular sulfonamide crystals. Sulfanilamide immediately stopped taking a lot of oral sodium bicarbonate, and Zhu Huanzhe more water.