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清胰汤中的白芍,大黄、黄苓和胡黄连水提液对大鼠胰蛋白酶和淀粉酶活力均有明显的抑制作用;芒硝能抑制大鼠胰腺泡分泌淀粉酶,但不影响酶的活力。结果提示清胰汤成分中含有的多种胰酶抑制剂可能是其治疗急性胰腺炎的有效因素。
White peony root, rhubarb, astragalus and Huhuanglian extracts from Qingyi Decoction all had obvious inhibitory effects on the activity of trypsin and amylase in rats; Glauberite could inhibit the secretion of amylase from rat pancreas, but it did not affect the enzyme. vitality. The results suggest that a variety of pancreatic enzyme inhibitors contained in Qingyitang may be an effective factor in the treatment of acute pancreatitis.