论文部分内容阅读
目的:探讨强化调脂对老年急性心肌梗死(AMI)患者远期预后的影响。方法:将我院老年AMI患者100例随机分为观察组和对照组,对照组给予常规剂量的调脂治疗,观察组给予强化调脂治疗,评估两组临床治疗效果及安全性。结果:治疗后观察组患者TC、TG、LDL-C、Hs-CRP及NT-proBNP明显优于对照组,两组比较差异具有统计学意义(P<0.05)。治疗后观察组患者LVEF、IVST、LVPWT、LVEDD明显优于对照组,两组比较差异具有统计学意义(P<0.05)。治疗后随访2年,观察组患者主要不良心血管事件的发生率明显低于对照组,两组比较差异具有统计学意义(P<0.05)。结论:强化调脂治疗对老年急性心肌梗死远期疗效显著,值得应用。
Objective: To investigate the effect of intensive lipid-lowering on the long-term prognosis of elderly patients with acute myocardial infarction (AMI). Methods: 100 elderly patients with AMI in our hospital were randomly divided into observation group and control group, the control group was given conventional dose of lipid-lowering therapy, the observation group was given intensive lipid-lowering therapy, and the clinical efficacy and safety of the two groups were evaluated. Results: TC, TG, LDL-C, Hs-CRP and NT-proBNP in the observation group were significantly better than those in the control group after treatment. There was significant difference between the two groups (P <0.05). After treatment, the LVEF, IVST, LVPWT and LVEDD in the observation group were significantly better than those in the control group. There was significant difference between the two groups (P <0.05). After 2 years of follow-up, the incidence of major adverse cardiovascular events in the observation group was significantly lower than that in the control group, with significant difference between the two groups (P <0.05). Conclusion: Intensive lipid-lowering therapy has a long-term curative effect on elderly patients with acute myocardial infarction and is worthy of application.