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目的了解大理州2006-2010年疑似预防接种异常反应监测,系统运转情况,评价大理州疑似预防接种异常反应(AEFI)监测和处理控制系统的运行状况。方法采用描述性流行病学方法对疑似预防接种异常反应测系统所收集的AEFI病例进行分析。结果全州共报告AEFI 78例,其中一般反应8例(10.26%),异常反应49例(62.82%),偶合症12例(15.38%),不明原因3例(3.85%),实施差错事故6例(7.69%)。在所使用的20种疫苗中有12种出现不良反应,以肺炎疫苗发生率最高。在报告的预防接种不良反应中,最常见的为过敏性皮疹(25.64%)。结论建立和完善规范化的预防接种AEFI监测系统,可提高不良反应报告的敏感性和利用率。加强预防接种规范化操作,准确掌握禁忌证,选用免疫效果好、且安全性高的疫苗,以减少预防接种不良反应的发生。
Objective To understand the monitoring and system operation of suspected immunization in Dali Prefecture from 2006 to 2010 and to evaluate the operation of AEFI monitoring and treatment control system in Dali Prefecture. Methods Descriptive epidemiological methods were used to analyze AEFI cases collected from suspected vaccination anomaly response system. Results A total of 78 AEFI cases were reported in the whole state. Among them, 8 were general reactions (10.26%), 49 were abnormal reactions (62.82%), 12 were intercourse (15.38%), 3 were unknown causes (3.85% Example (7.69%). Twelve of the 20 vaccines used showed adverse reactions, with the highest incidence of pneumonia vaccine. Of the reported adverse effects of vaccination, the most common was an allergic skin rash (25.64%). Conclusion Establishing and perfecting standardized AEFI vaccination monitoring system can improve the sensitivity and utilization of adverse reaction reports. Strengthen the standardized operation of vaccination, accurately grasp the contraindications, the selection of vaccines with good immunization, and high safety, in order to reduce the occurrence of adverse effects of vaccination.