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高原环境的特点是缺氧,未经习服人员快速从平原进入高原地区时,往往会出现头痛、恶心、厌食、肠胃不适、睡眠不佳等急性高原病症状,常见的高原病包括急性高原反应、高原脑水肿、高原肺水肿等。乙酰唑胺是常见的碳酸酐酶(CA)抑制药,是唯一被美国FDA批准用于防治急性高原病的药物。现将乙酰唑胺预防和治疗高原病的研究进展综述如下。1防治急性高原反应阶梯习服锻炼可减少急性高原反应的发生,但在
High altitude environment is characterized by hypoxia, unassisted personnel to quickly enter the plateau from the plains, often appear headache, nausea, anorexia, stomach upset, poor sleep and other symptoms of acute altitude sickness, common high altitude sickness, including acute altitude sickness , High altitude brain edema, high altitude pulmonary edema. Acetazolamide is a common carbonic anhydrase (CA) inhibitor and is the only drug approved by the U.S. FDA for the prevention and treatment of acute mountain sickness. Now acetazolamide prevention and treatment of altitude sickness research advances are summarized below. 1 prevention and treatment of acute altitude sickness acclimation exercise can reduce the incidence of acute altitude sickness, but in