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目的探讨内镜下卢戈氏液染色诊断食管早期癌和癌前病变的价值。方法对46例食管黏膜病变者行内镜下卢戈氏液染色,比较食管病变及着色范围,对黏膜不染色区多点活检,病理诊断为鳞状上皮重度不典型增生者行内镜黏膜切除术(EEMR),诊断为鳞状细胞癌者经超声微探头检查证实为黏膜内癌,予以黏膜下剥离切除。结果46例患者中,15例患者存在18处黏膜不染色区,其中上皮单纯增生3处,轻度不典型增生4处,中度不典型增生6处,重度不典型增生4处,鳞状细胞癌1处。结论卢戈氏液染色法是诊断早期食管癌及癌前病变实用的方法,可提高食管癌前病变和早期食管癌检出率。
Objective To investigate the value of endoscopic Lurgotic fluid staining in the diagnosis of early esophageal cancer and precancerous lesions. Methods Forty-six patients with esophageal mucosal lesions underwent endoscopic Lurgotic fluid staining. The esophageal lesions and coloration range were compared. Multiple biopsies were performed on mucosal non-stained areas. Pathological diagnosis was made by endoscopic mucosal resection of patients with severe atypical squamous hyperplasia Surgery (EEMR), diagnosed with squamous cell carcinoma by ultrasound microprobe examination confirmed intramucosal cancer, submucosal dissection resection. Results Among the 46 patients, there were 18 mucosal non-staining regions in 15 patients, including 3 epithelial hyperplasia, 4 mild dysplasia, 6 moderate dysplasia, 4 severe dysplasia and 5 squamous cell 1 cancer. Conclusion Loutot’s staining method is a practical method to diagnose early esophageal cancer and precancerous lesions, and can improve the detection rate of esophageal precancerous lesions and early esophageal cancer.