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高浓度葡萄糖可增加内皮细胞内反应性导其凋亡;银杏叶提取物可提高内皮细胞在高糖环境下的活力,降低其凋亡率,可能与其通过抗氧化作用及下调泛素介导的胞浆内蛋白水解系统有关。
High concentration of glucose can increase the reactivity of endothelial cells to induce apoptosis; Ginkgo biloba extract can increase the activity of endothelial cells in high glucose environment and reduce their apoptosis rate, probably through its antioxidation and down regulation of ubiquitin-mediated Intracytoplasmic proteolysis system is involved.