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目的:研究旨在评估中西医结合治疗老年患者全身麻醉术后认知功能障碍的临床效果。方法:2012年1月—2015年12月,在该院接受全身麻醉的非心脏外科手术后发生轻度认知功能障碍的患者120例,根据治疗方法的不同,将其分为对照组和观察组,每组各60例,对照组的患者接受了常规西医治疗,观察组的患者在常规西医治疗的基础上,采用补肾益气活血化痰方剂治疗,分别于术前、术后7 d以及术后14 d对患者的认知功能进行评价。结果:两组患者在术前和术后7 d的MMSE和MOCA得分差异无统计学意义(P>0.05);第14天的MMSE和MOCA得分差异有统计学意义(P<0.05),观察组的MMSE和MOCA得分明显高于对照组(P<0.05)。结论:中西医结合治疗可以有效地改善全身麻醉后的认知功能障碍,值得在临床大力推广应用。
OBJECTIVE: To study the clinical efficacy of traditional Chinese and western medicine in the treatment of cognitive dysfunction after general anesthesia in elderly patients. Methods: From January 2012 to December 2015, 120 patients with mild cognitive impairment after general anesthesia undergoing non-cardiac surgery in this hospital were divided into control group and observation group according to the different treatment methods Group, 60 cases in each group. Patients in the control group received conventional western medicine. Patients in the observation group were treated with the method of tonifying the kidney, invigorating the blood and invigorating the blood and invigorating the phlegm respectively on the basis of routine western medicine treatment. The patients in the observation group were treated preoperatively, The patient’s cognitive function was evaluated 14 days after operation. Results: There was no significant difference in MMSE and MOCA scores between the two groups before and 7 days after operation (P> 0.05). On the 14th day, MMSE and MOCA scores were significantly different (P <0.05) MMSE and MOCA scores were significantly higher than the control group (P <0.05). Conclusion: The combination of traditional Chinese and Western medicine can effectively improve the cognitive dysfunction after general anesthesia, it is worth to clinically promote.