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目的对伊宁市2013年135例阴性静脉吸毒人群队列展开研究活动,分析吸毒人群危险因素。方法选取2013年内医院检测HIV阴性的吸毒人群队列135人,对队列内所有人每3个月随访调查高危吸毒行为以及性行为情况,并采集血样进行艾滋病、丙肝、梅毒抗体检测。结果随访调查1年,135例静脉吸毒人群中有23人失访、11人提前中止调查,仅有101人坚持随访,队列保持率为74.8%。艾滋病抗体阳性2例,HIV阳性率为2.0%,通过条件分析发现,安全套的使用、性伴侣吸毒与HIV抗体转阳有统计学意义(P<0.05);丙肝抗体阳性47例,HCV阳性率为46.5%,通过条件分析发现,吸毒与HCV抗体转阳有统计学意义(P<0.05);梅毒抗体阳性2例,RPR阳性率为2.0%,通过条件分析发现,性别与RPR抗体转阳有统计学意义(P<0.05)。结论通过伊宁市静脉吸毒人群队列调查发现,吸毒人群中的丙肝发生率较高,需要针对其危险因素进行对照干预,以遏制传染性病毒的传播速度。
Objective To investigate the cohort of 135 negative intravenous drug users in Yining City in 2013 and analyze the risk factors of drug addicts. Methods A total of 135 HIV-negative drug addicts in our hospital were enrolled in our hospital in 2013. All the patients in the cohort were followed up every 3 months to investigate the behavior of high-risk drug addicts and their sexual behaviors. Blood samples were collected for the detection of AIDS, hepatitis C and syphilis antibodies. Results One year follow-up survey, 23 out of 135 intravenous drug users were lost to follow-up, 11 were terminated earlier and only 101 were followed up. The cohort retention rate was 74.8%. HIV antibody positive in 2 cases, HIV positive rate of 2.0%, through the condition analysis found that the use of condoms, sexual partners drug use and HIV antibody transfer of the sun was statistically significant (P <0.05); hepatitis C antibody positive in 47 cases, the positive rate of HCV 46.5%. Through conditional analysis, it was found that there was a significant difference (P <0.05) between drug use and HCV antibody transfection. Two cases were positive for syphilis antibody and the positive rate of RPR was 2.0%. According to the condition analysis, Significance (P <0.05). Conclusion According to the cohort survey of intravenous drug users in Yining City, it is found that the incidence of hepatitis C in drug addicts is relatively high. Therefore, a controlled intervention on the risk factors is needed to stop the spread of infectious virus.