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为了阐明白血病患儿为何会发生长期感染,近日来自圣犹大儿童医院的研究人员通过研究发现了一种特殊突变,该突变能够让细菌对有效的抗生素疗法产生耐受性,相关研究刊登于国际杂志mBio上。研究者Jason Rosch指出,我们的研究阐明了细菌抗生素耐药性产生的一种新机制,当然也为临床治疗带来了一定挑战,同时这种细菌抗生素耐药的情况也在化疗引发的免疫系统损伤的患者中会经常出现。这种状况出现在一名仅6周大患急性髓性白血病的患儿身上,研究人员利用癌症疗法清除掉了患儿机体的白细胞,白细胞能够帮助机体抵
To clarify why chronic leukemia patients develop chronic infection, researchers from St. Jude Children’s Hospital recently found that a mutation that allows bacteria to tolerate effective antibiotic therapy has been published in international journals mBio on. Jason Rosch, a researcher, points out that our study illustrates a new mechanism of antibiotic resistance in bacteria, which of course poses some challenges for clinical treatment, as well as the antibiotic resistance of the bacteria in the immune-triggered immune system Damaged patients often appear. This condition occurs in a patient with acute myeloid leukemia, which is only 6 weeks old. Researchers use cancer therapies to clear the body’s white blood cells that help the body to resist