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目的研究子宫内膜息肉采用宫腔镜手术治疗的效果及预防术后复发的价值。方法选取2011年9月—2013年5月于苏州市中西医结合医院进行手术治疗的90例子宫内膜息肉患者为研究对象,将其随机分为对照组和观察组,各45例。比较两组患者的并发症发生率、术中出血量、复发率及治疗前后的月经量、组织血管内皮生长因子(VEGF)、雌激素受体(ER)及孕激素受体(PR)表达情况。结果观察组患者术中出血量为(18.3±2.0)ml,少于对照组的(26.4±2.5)ml,术后0.5年及1年复发率均低于对照组,差异均有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。治疗前两组患者月经量、组织VEGF、ER及PR表达比较,差异无统计学意义(P>0.05),而治疗后3个月及6个月观察组患者月经量少于对照组,组织VEGF、ER及PR表达均低于对照组,差异有统计学意义(P<0.05)。结论子宫内膜息肉采用宫腔镜手术治疗效果较好,且有助于控制患者术后复发。
Objective To study the effect of hysteroscopic surgery on endometrial polyps and the value of preventing postoperative recurrence. Methods Ninety patients with endometrial polyps who underwent surgical treatment at Suzhou Hospital of Integrated Traditional Chinese and Western Medicine from September 2011 to May 2013 were selected and randomly divided into control group and observation group, 45 cases in each group. The complication rate, intraoperative blood loss, recurrence rate, menstrual flow before and after treatment, expression of vascular endothelial growth factor (VEGF), estrogen receptor (ER) and progesterone receptor (PR) were compared between the two groups . Results The intraoperative blood loss in observation group was (18.3 ± 2.0) ml, less than that in control group (26.4 ± 2.5) ml, and the recurrence rates at 0.5 and 1 year after operation were both lower than those in control group P <0.05). There was no significant difference in the complication rates between the two groups (P> 0.05). There was no significant difference in the menstrual flow, the expression of VEGF, ER and PR in the two groups before treatment (P> 0.05), while the menstrual flow in the observation group was less than that in the control group at 3 and 6 months after treatment , ER and PR expression were lower than the control group, the difference was statistically significant (P <0.05). Conclusion Endometrial polyps using hysteroscopic surgery is better, and help to control postoperative recurrence.