子宫内膜神经内分泌癌(NECa)是一种罕见的肿瘤。作者分析了25例该肿瘤的临床病理特点。患者年龄范围37~87岁(中位年龄57岁),最常见的临床症状表现为阴道出血。10例为单纯性NECa,15例混合有其它组织学类型,最常见混合的是子宫内膜样腺癌。NECa其中包括大细胞型15例,小细胞型4例,混合型6例。89%的转诊/会诊病例意识到NECa的存在。所有肿瘤≥1项神经内分泌标志物阳性 Endometrial neuroendocrine carcinoma (NECa) is a rare tumor. The authors analyzed the clinical and pathological features of 25 cases of this tumor. Patients ranged in age from 37 to 87 years (median 57 years). The most common clinical symptom was vaginal bleeding. Ten cases were simple NECa, 15 cases mixed with other histological types, the most common mixed endometrial adenocarcinoma. NECa included 15 cases of large cell type, 4 cases of small cell type and 6 cases of mixed type. 89% of referral / consultation cases recognize the existence of NECa. All tumors ≥ 1 neuroendocrine marker positive