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目的分析1990-2011年玉溪市暗娼(FSWs)人群HIV-1感染态势,旨在合理估算HIV-1在玉溪市暗娼中的流行态势。方法对1990-2011年玉溪市相关场所的暗娼用HIV-1 BED捕获酶免疫测定法(BED-CEIA)和微量HIV-1抗体明胶颗粒凝聚法(ML-PA)进行HIV-1新发感染率检测,并采用ML-PA和BED-CEIA对HIV-1新近感染态势进行估算。结果共计纳入样本20 288份,检出HIV-1阳性214份,1990-1996年感染率均为0,1997-2011年为0.61%~1.40%,流行趋势差异有统计学意义(P<0.05)。HIV-1新发感染率:ML-PA法2006-2011年为0.00~2.31/1 000人年,BED-CEIA法2005-2011年为0.00~5.89/1 000人年,流行趋势差异无统计学意义(P>0.05)。结论玉溪市暗娼人群艾滋病流行处于较低水平,且呈下降趋势,两种检测方法的结论一致,但缺乏一致性。
Objective To analyze the trend of HIV-1 infection in FSWs from 1990 to 2011 in order to estimate the prevalence of HIV-1 in female sex workers in Yuxi City. Methods The prevalence of HIV-1 infection among commercial sex workers in Yuxi City from 1990 to 2011 was determined by HIV-1 BED capture enzyme immunoassay (BED-CEIA) and micro-HIV-1 antibody gelatin particle agglutination (ML-PA) The recent HIV-1 infection status was estimated using ML-PA and BED-CEIA. Results A total of 20 288 samples were collected and 214 were positive for HIV-1. The infection rates were 0 in 1990-1996 and 0.61% -1.40% in 1997-2011. The prevalence trends were statistically significant (P <0.05) . The prevalence of HIV-1 infection was 0.00 to 2.31 per 1,000 person-years in the ML-PA method from 2006 to 2011, and 0.00 to 5.89 per 1,000 person-years in the BED-CEIA method between 2005 and 2011. There was no statistical difference in the prevalence trends between the two groups Significance (P> 0.05). Conclusion The prevalence of HIV / AIDS among FSWs in Yuxi City is at a low level and shows a decreasing trend. The two detection methods have the same conclusion but lack of consistency.