目的观测在碘缺乏病（IDD）严重流行且推广加碘盐困难的特殊病区，推广碘控释器土盐水加碘防治IDD效果。方法随机抽样检查和田地区各县市农牧区居民使用碘控释器情况及其防治效果。结果推广后第3个月和第15个月，和田地区农牧民碘控释器使用率分别为74．4％和70．3％；碘控释器加碘土盐水含碘量为6．6mg／L；8～10岁儿童平均尿碘加碘前仅59μg／L，加碘四个月上升到205μg／L，连续加碘到第21个月为238μg／L；加碘前甲状腺肿大率为51．2％，Ⅱ°肿大率为11．9％；加碘15个月甲状腺肿大率为32．3％，Ⅱ°肿大率为6．2％；甲状腺肿大率均显著降低（P＜0．01）。结论碘控释器土盐水加碘防治IDD，顺应农牧民用盐习惯，多数居民开始使用；尿碘短期内可达适宜水平，且长期稳定，防治效果良好，可在适用地区组织推广。 Objective To observe the special prevalence of idiopathic iodine deficiency (IDD) epidemic and promote the iodized salt difficult to promote the IDD effect. Methods A random sample was used to examine the use of iodine-controlled releasers by residents in rural areas and pastoral areas in Hetian and its control effects. Results The third and the fifth months after the popularization, the utilization rates of iodine-controlled releasers of peasants and herdsmen in Hetian were 74.4% and 70.3%, respectively; and iodine controlled-release iodine brine contained 6 iodine. 6 mg / L; children aged 8-10 years had an average urinary iodine of 59 μg / L before iodine addition, 205 μg / L within four months of iodine addition, and 238 μg / L after 21 months of continuous iodine treatment; Rate was 51.2%, Ⅱ degree enlargement rate was 11.9%; goiter 15 months goiter rate was 32.3%, Ⅱ ° enlargement rate was 6.2%; goiter rate was significantly Decreased (P <0.01). Conclusion Iodine-controlled soil salt water iodine control IDD, follow the salt habits of farmers and herdsmen, most residents began to use; urinary iodine up to the appropriate level in the short term, and long-term stability, control effect is good, can be organized and popularized in applicable areas.