生长激素缺乏症(GHD)是儿童生长迟缓(矮身材)的常见病因,1956年首次从人垂体中成功分离及提纯了人垂体生长激素(phGH),成为GH研究的标志性进展。1958年phGH用于治疗首例GHD患儿并成功地获得促生长疗效。但是,于1962~1985年3000例接受过phGH治疗的患儿中150例不幸染上Creutzfeld Growth hormone deficiency (GHD) is a common cause of growth retardation (short stature) in children. For the first time, the human pituitary growth hormone (phGH) was isolated and purified from human pituitary for the first time in 1956, becoming a landmark progress in the study of GH. In 1958, phGH was used to treat the first child with GHD and successfully achieved the growth-promoting effect. However, 150 of the 3,000 children with phGH treated from 1962 to 1985 were unfortunately infected with Creutzfeld