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目的 探讨低水平 β HCG滋养细胞肿瘤的临床特点、诊断及对策。 方法 回顾性分析汕头大学医学院第一附属医院 1 991年 1月至 2 0 0 3年 1月间 6例低水平β HCG滋养细胞肿瘤的临床特点及诊治经过。 结果 6例中侵蚀性葡萄胎 3例 ,绒癌 2例 ,胎盘部位滋养细胞肿瘤 (PSTT) 1例。先行妊娠葡萄胎 3例 ,足月产 3例 ;先行妊娠至诊断时间 2～ 1 8个月 ;5例主要表现为不规则阴道出血 ,5例超声提示滋养细胞肿瘤 ;血 β HCG 1 1～2 7IU/L。结论 低水平 β HCG滋养细胞肿瘤可能与滋养细胞的类型及分布有关 ,其临床特点主要为不规则阴道出血 ,超声是诊断及鉴别诊断的主要手段 ,早期诊断、积极治疗有利于防止病情恶化
Objective To investigate the clinical features, diagnosis and countermeasures of low-level β-HCG trophoblastic tumor. Methods The clinical features, diagnosis and treatment of 6 cases of low-level β-HCG trophoblastic tumor in the First Affiliated Hospital of Shantou University Medical College from January 1991 to January 2003 were retrospectively analyzed. Results There were 3 cases of invasive hydatidiform mole, 2 cases of choriocarcinoma and 1 case of placental trophoblastic tumor (PSTT) in 6 cases. 3 cases of preeclamptic hydatidiform mole, 3 cases of full-term pregnancy; first trimester of pregnancy to diagnosis time of 2 to 18 months; 5 cases of irregular vaginal bleeding, 5 cases of tonic gestational trophoblastic tumor; blood β HCG 1 1 ~ 2 7IU / L. Conclusions Low-level β-HCG trophoblastic tumor may be related to the type and distribution of trophoblast cells. The main clinical features are irregular vaginal bleeding. Ultrasound is the main method of diagnosis and differential diagnosis. Early diagnosis and aggressive treatment are helpful to prevent the disease from deteriorating