目的探讨C反应蛋白(CRP)在男性附性腺慢性炎症诊疗中的临床意义。方法采集41例慢性前列腺炎、附睾炎、精囊炎患者精浆进行CRP测定,与77例其他不育症患者和31例有生育能力的正常男性精浆CRP进行对照,并对病例组病人治疗前后的精浆CRP进行对比。结果(1)病例组精浆CRP(69.55±23.16)mg/L,不育组与生育组精浆CRP分别为(3.82±2.67)mg/L、(4.55±3.62)mg/L。病例组精浆CRP显著高于不育组与生育组(P<0.01);(2)病例组治疗后精浆CRP明显下降,接近正常。结论精浆CRP测定在男性附性腺慢性炎症诊疗中有重要临床意义。 Objective To investigate the clinical significance of C-reactive protein (CRP) in diagnosis and treatment of chronic gonadal inflammation in men. Methods CRP was measured in 41 patients with chronic prostatitis, epididymitis and seminal vesicle, and compared with CRP in 77 other infertile patients and 31 fertile normal male seminal plasma. The serum levels of CRP in the patients before and after treatment Of seminal plasma CRP. Results (1) CRP in the seminal plasma was (69.55 ± 23.16) mg / L in the case group and (3.82 ± 2.67) mg / L in the sterile group and (4.55 ± 3.62) mg / L in the reproductive group. CRP in the seminal plasma was significantly higher in the case group than in the sterile group and the reproductive group (P <0.01). (2) The CRP in the seminal plasma in the case group decreased significantly, approaching normal. Conclusion The determination of seminal plasma CRP has important clinical significance in the diagnosis and treatment of male chronic gonadal inflammation.