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目的提高对咳嗽变异性哮喘(CVA)的诊治水平。方法对本院2001年7月~2004年12月诊断为儿童咳嗽变异性哮喘的90例患儿的临床资料进行回顾性分析。结果CVA患儿均有持续或反复发作性咳嗽症状,无喘息,有明显诱因及家族过敏史,肺部检查无阳性体征,抗生素治疗无效;给予吸入糖皮质激素普米克气雾剂、口服β2受体激动剂博利康尼及抗过敏药酮替酚药物治疗,疗程均为6个月,疗效显著,治疗过程中未见明显的毒副作用。结论对慢性咳嗽应用抗生素疗效差,在排除了其他器质性疾病后应考虑CVA,采取诊断性治疗等手段以确诊;吸入糖皮质激素、口服β2受体激动剂及抗过敏药物治疗,效果满意。
Objective To improve the diagnosis and treatment of cough variant asthma (CVA). Methods The clinical data of 90 children with cough variant asthma diagnosed as children from July 2001 to December 2004 in our hospital were analyzed retrospectively. Results All children with CVA had persistent or recurrent cough symptoms, no wheezing, obvious causes and family history of allergy, no positive signs in lung examination and no antibiotic treatment. Inhaled glucocorticoid pulmicort aerosol, oral β2 Body agonist Boli Kang Ni and anti-allergy ketotifen drug treatment, treatment of 6 months, a significant effect, no obvious side effects during the treatment. Conclusions The curative effect of antibiotics on chronic cough is poor. CVA should be considered after excluding other organic diseases. Diagnostic treatment should be taken to confirm the diagnosis. Inhalation of glucocorticoid, oral β2 receptor agonist and anti-allergic drugs is satisfactory .