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川崎病(Kawasaki disease)又名皮肤粘膜淋巴结综合征(Mucocutaneos lymph node Syndrome),是小儿常见的急性发热出疹性疾病。发病遍及全世界。近年来发现本病患儿心血管系统广泛受累,包括全身血管炎、全心脏炎,尤其是冠状动脉炎可形成冠状动脉瘤、血栓栓塞,从而导致缺血性心脏病、心肌梗塞,猝死,因此日益受到重视。有人指出当今川崎病已取代风湿热,成为小儿后天性心脏病的主要病种。病因和发病的机理 1967年日本川崎富作首次报告本病,以后世界各地均有报告。最近中国报告病例增多。患者以罂幼儿较多见,1~5岁占患儿总
Kawasaki disease, also known as Mucocutaneos lymph node syndrome, is a common acute fever and rash disease in children. The incidence of all over the world. In recent years, the patient’s cardiovascular system found extensive involvement, including systemic vasculitis, total heart disease, especially coronary artery disease can form coronary aneurysm, thromboembolism, leading to ischemic heart disease, myocardial infarction, sudden death, therefore Increasing attention. It has been pointed out that today Kawasaki disease has replaced rheumatic fever as a major congenital heart disease in children. Etiology and pathogenesis The Kawasaki, Japan in 1967 for the first time reported the disease, the disease has been reported around the world. China recently reported an increase in cases. Poppy child patients to see more, 1 to 5 years old accounted for the total children