直接将溶血栓药投到冠状动脉内的局部纤溶疗法,因要采用冠状动脉插管,其血流再通的效果容易制定,但经静脉应用溶血栓药的全身纤溶疗法,不一定采用冠脉插管,故需要确定血流再通效果的指标。有报告说,根据reperfusion arrhythmia、心电图ST改变和肌酸激酶(CK)达到峰值的时间等可以推测血流的再通,但对某个具体的的病例难于作出判断的情况也不少。笔者等注意到溶血栓疗法中,血循重建成功后CK急速流到血液中的“冲洗”(wash out)现象,本文探讨是否能通过洋细观察血循重建极早期CK的流出情况,来判断血流再通的效果。考虑到过去CK测定是从收入CCU起每3小时一次,这不利于充分观察 Thrombolytic drugs directly into the local intra-coronary fibrinolysis, due to the use of coronary artery catheterization, the effect of recanalization is easy to formulate, but intravenous thrombolytic systemic fibrinolysis, not necessarily used Coronary catheterization, it needs to determine the effect of blood flow through the index. It has been reported that the reperfusion of blood flow can be presumed based on reperfusion arrhythmia, change of electrocardiogram ST, and peak time of creatine kinase (CK). However, it is difficult to judge a specific case in many cases. The author noticed that in the thrombolytic therapy, the phenomenon of “wash-out” of CK rapidly flowing into the blood after the success of blood circulation reconstruction was explored, and whether this can be judged by observing the outflow of extremely early CK by blood-flow reconstruction The effect of recanalization. Taking into account the past CK measurement from the income of CCU since every 3 hours, which is not conducive to full observation