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本文对比统计了皮质醇增多症64例及疑诊皮质醇增多症113例的非创伤性检测手段的敏感度、特异度,认为:①尿17-(OH)CS、17-KS及血浆皮质醇测定作为筛选手段是不理想的。②大剂量地塞米松抑制试验确是识别皮质醇增多症及区分类型的有效方法。特别指出尿的17-(OH)CS值在正常范围时,抑制率小于50%似有较高的准确度(约95%)。③形态学诊断上,CT显著优于B超,然而,CT价格昂贵且有放射性损伤,尚未广泛普及。B超仍做为首选手段,但需加强超声诊断医师专业队伍的建设。
In this paper, we compared the sensitivity and specificity of non-traumatic testing methods of 64 cortisol hypersensitivity and 113 suspected cortisol hyperaemia. It is concluded that: ① Urine 17- (OH) CS, 17-KS and plasma cortisol The assay is not ideal as a screening tool. ② high-dose dexamethasone inhibition test is indeed an effective way to identify cortisol hypersecretion and type of distinction. Specially pointed out that urinary 17- (OH) CS value in the normal range, the inhibition rate of less than 50% seems to have higher accuracy (about 95%). ③ morphological diagnosis, CT was significantly better than the B-, however, CT is expensive and has radioactive damage, has not yet been widely available. B-still as the preferred method, but need to strengthen the construction of the professional team of ultrasonic diagnosis physicians.